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Using Polio to Treat Aggressive Brain Cancer

Using Polio to Treat Aggressive Brain Cancer
July 03
16:19 2018

follow url When I was a boy in the 1950s (yes, I’m THAT old), the mention of polio was more frightening than cancer. As a kid, you only thought of older people getting cancer, but polio crippled kids and lots of kids. In first grade, there was a girl in our class that had metal braces on both of the legs because of polio. Sadly, many of the kids teased her and made her cry. She couldn’t run or play in most of the things that rest of us did and I remember I felt sad for her. When I heard that she had polio, it made me really scared of the disease. The next year, we were told that the girl died from her polio and that made us even more frightened of catching the dreaded disease.

In school, we studied all of the presidents and that’s when I learned that President Franklin D. Roosevelt was crippled with polio and that he eventually died as a result of his polio.

500mg amoxil I still remember hearing the news broadcast that some doctor had developed a vaccine to prevent polio. Everyone was talking about it and a couple of years later, all of us school kids were given a polio vaccine. Everyone said that this doctor (Jonas Salk) was a miracle worker and that he would save the lives of tens of thousands of girls, boys and adults.

Polio is the common name for poliomyelitis. It is caused by the poliovirus and is passed to others by contact with the saliva or fecal material of an infected person. It can be highly contagious, so precautions should always be taken to avoid having an infected person cough or sneeze on you or if they haven’t properly washed their hands after having a bowel movement and you touch their infected hands and then without realizing it, you touch your mouth.

The virus infects the brain and spinal cord, which can result in muscle weakness of the legs and even paralysis.

How does one know they have polio? Believe it or not, about 72% of those infected will have no visible symptoms early on. Others will develop a sore throat, fever, tiredness, nausea, headache and stomach pain. (The day FDR died, he complained of an intense headache and then slumped over in his chair and died later that afternoon of what the doctor said was a massive cerebral (brain) hemorrhage.)

If polio is so dangerous, how in the world could it be used to treat brain cancer?

According to Fox News:

“Some 21 percent of patients with advanced brain cancer treated with a modified polio vaccine were alive after three years, compared with 4 percent of patients with similar tumors who received standard therapies, U.S. researchers said on Tuesday.”

“The findings, published online in the New England Journal of Medicine, are the latest update on an experimental cancer vaccine developed at Duke Cancer Institute in Durham, North Carolina, for patients with glioblastoma, a deadly form of brain cancer. “

“For most patients whose glioblastoma has recurred after treatment, the average survival is 12 months. Treatment typically involves a mix of surgery, chemotherapy, radiation and targeted treatments.”

“The experimental vaccine involves a genetically modified form of polio, which is infused into the brain tumor through a surgically implanted catheter. The vaccine works by provoking the immune system to specifically target tumor cells.”

Glioblastoma is an aggressive type of brain cancer and is usually fatal. Former Sen. Ed Kenney died of glioblastoma and this is the same kind of cancer that Sen. John McCain is suffering from now. Beau Biden, son of former Vice President Jo Biden also died from a type of glial brain cancer.

This finding is far from being a total cure or treatment, but it does show great promise in extending the lives of those diagnosed with one of the most aggressive forms of brain cancer known. Don’t know about you, but 21% is better odds than 4%.

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